Pharmacologic limits of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity.

Polyaspartic acid (PAA) ameliorates experimental gentamicin nephrotoxicity despite marked accumulation of gentamicin in the renal cortex. The experiments described here probe the extent of PAA's nephroprotective action when increasing doses of gentamicin, in excess of an established nephrotoxic dose...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Swan, S K, Gilbert, D N, Kohlhepp, S J, Kohnen, P W, Bennett, W M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187666/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8452369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.2.347
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