Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine.

The (S)- and (R)-enantiomers of acyclic purine nucleoside phosphonate analogs (i.e., 3-hydroxy-2-phosphonomethoxypropyl [HPMP] derivatives, 3-fluoro-2-phosphonomethoxypropyl [FPMP] derivatives, and 2-phosphonomethoxypropyl [PMP] derivatives of adenine [A], 2-aminopurine, 2,6-diaminopurine [DAP], and...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Balzarini, J, Holy, A, Jindrich, J, Naesens, L, Snoeck, R, Schols, D, De Clercq, E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8452366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.2.332
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