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The G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila
Signaling by Smoothened (Smo) plays fundamental roles during animal development and is deregulated in a variety of human cancers. Smo is a transmembrane protein with a heptahelical topology characteristic of G protein-coupled receptors. Despite such similarity, the mechanisms regulating Smo signalin...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876555/ https://ncbi.nlm.nih.gov/pubmed/17483466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702374104 |
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