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Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data

The cytoskeletal protein, actin, has its structure and function regulated by cofilin. In the absence of an atomic resolution structure for the actin/cofilin complex, the mechanism of cofilin regulation is poorly understood. Theoretical studies based on the similarities of cofilin and gelsolin segmen...

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Bibliographic Details
Main Authors: Kamal, J. K. Amisha, Benchaar, Sabrina A., Takamoto, Keiji, Reisler, Emil, Chance, Mark R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876546/
https://ncbi.nlm.nih.gov/pubmed/17470807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611283104
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