Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

BACKGROUND: Since the majority of apolipoprotein E (apoE) existing in the cerebrospinal fluid is associated with high-density lipoprotein (HDL), one should focus on the role of the apoE-HDL complex rather than on that of free apoE in cholesterol metabolism in the central nervous system. However, the...

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Detalhes bibliográficos
Main Authors: Gong, Jian-Sheng, Morita, Shin-ya, Kobayashi, Mariko, Handa, Tetsurou, Fujita, Shinobu C, Yanagisawa, Katsuhiko, Michikawa, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876452/
https://ncbi.nlm.nih.gov/pubmed/17504523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-2-9
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