Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer

BACKGROUND: Loss of BIN1 tumor suppressor expression is abundant in human cancer and its frequency exceeds that of genetic alterations, suggesting the role of epigenetic regulators (DNA methylation). BIN1 re-expression in the DU145 prostate cancer cell line after 5-aza-2'-deoxycytidine treatmen...

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Detalhes bibliográficos
Main Authors: Kuznetsova, Ekaterina B, Kekeeva, Tatiana V, Larin, Sergei S, Zemlyakova, Valeria V, Khomyakova, Anastasiya V, Babenko, Olga V, Nemtsova, Marina V, Zaletayev, Dmitry V, Strelnikov, Vladimir V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876449/
https://ncbi.nlm.nih.gov/pubmed/17477881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-6-9
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