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Biphasic role for Wnt/β-catenin signaling in cardiac specification in zebrafish and embryonic stem cells

Understanding pathways controlling cardiac development may offer insights that are useful for stem cell-based cardiac repair. Developmental studies indicate that the Wnt/β-catenin pathway negatively regulates cardiac differentiation, whereas studies with pluripotent embryonal carcinoma cells suggest...

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Detalhes bibliográficos
Main Authors: Ueno, Shuichi, Weidinger, Gilbert, Osugi, Tomoaki, Kohn, Aimee D., Golob, Jonathan L., Pabon, Lil, Reinecke, Hans, Moon, Randall T., Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876428/
https://ncbi.nlm.nih.gov/pubmed/17522258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702859104
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