High-level mupirocin resistance in Staphylococcus aureus: evidence for two distinct isoleucyl-tRNA synthetases.

Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four highly r...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Gilbart, J, Perry, C R, Slocombe, B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8431015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.1.32
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