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Novel PAX6 Binding Sites in the Human Genome and the Role of Repetitive Elements in the Evolution of Gene Regulation

Pax6 is a critical transcription factor in the development of the eye, pancreas, and central nervous system. It is composed of two DNA-binding domains, the paired domain (PD), which has two helix–turn–helix (HTH) motifs, and the homeodomain (HD), made up from another HTH motif. Each HTH motif can bi...

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Detalhes bibliográficos
Publicado no:Genome Res
Principais autores: Zhou, Yi-Hong, Zheng, Jessica B., Gu, Xun, Saunders, Grady F., Yung, W.-K. Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12421758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.188302
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