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Conservation of the Biotin Regulon and the BirA Regulatory Signal in Eubacteria and Archaea

Biotin is a necessary cofactor of numerous biotin-dependent carboxylases in a variety of microorganisms. The strict control of biotin biosynthesis in Escherichia coli is mediated by the bifunctional BirA protein, which acts both as a biotin–protein ligase and as a transcriptional repressor of the bi...

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Bibliographic Details
Main Authors: Rodionov, Dmitry A., Mironov, Andrei A., Gelfand, Mikhail S.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC187538/
https://ncbi.nlm.nih.gov/pubmed/12368242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.314502
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