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Aminoguanidine prevents age-related arterial stiffening and cardiac hypertrophy

Aging is associated with cardiac hypertrophy and arterial stiffening possibly associated with accumulation of advanced glycation end products (AGEs). We evaluated the effect of aminoguanidine, an inhibitor of AGE production, on end-stage alterations of renal and cardiovascular systems. Normotensive...

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Main Authors: Corman, Bruno, Duriez, Micheline, Poitevin, Pierre, Heudes, Didier, Bruneval, Patrick, Tedgui, Alain, Levy, Bernard I.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18752/
https://ncbi.nlm.nih.gov/pubmed/9448326
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