Pathogenic chaperone-like RNA induces congophilic aggregates and facilitates neurodegeneration in Drosophila

Protein aggregation is a hallmark of many neurodegenerative diseases. RNA chaperones have been suggested to play a role in protein misfolding and aggregation. Noncoding, highly structured RNA recently has been demonstrated to facilitate transformation of recombinant and cellular prion protein into p...

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Detalhes bibliográficos
Main Authors: Savvateeva-Popova, Elena, Popov, Andrei, Grossman, Abraham, Nikitina, Ekaterina, Medvedeva, Anna, Peresleni, Alexander, Korochkin, Leonid, Moe, James G., Davidowitz, Eliot, Pyatkov, Konstantin, Myasnyankina, Elena, Zatsepina, Olga, Schostak, Natalia, Zelentsova, Elena, Evgen'ev, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2007
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874921/
https://ncbi.nlm.nih.gov/pubmed/17441503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-222R.1
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