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Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation

The protein antizyme is a negative regulator of intracellular polyamine levels. Ribosomes synthesizing antizyme start in one ORF and at the codon 5′ adjacent to its stop codon, shift +1 to a second and partially overlapping ORF which encodes most of the protein. The ribosomal frameshifting is a sens...

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Autors principals: Ivanov, Ivaylo P., Atkins, John F.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874602/
https://ncbi.nlm.nih.gov/pubmed/17332016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm035
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