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New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses
Recent studies have demonstrated that in peripheral lymphoid tissues of normal mice and healthy humans, 1% to 5% of αβ T-cell receptor–positive (TCR(+)) T cells are CD4(−)CD8(−) (double-negative [DN]) T cells, capable of down-regulating immune responses. However, the origin and developmental pathway...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874581/ https://ncbi.nlm.nih.gov/pubmed/17197428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-050625 |
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