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Validation of a new fluorogenic real-time PCR assay for detection of CYP2C9 allelic variants and CYP2C9 allelic distribution in a German population

AIMS: The aim was to develop a fast detection method for the polymorphic alleles related to impaired CYP2C9-mediated metabolism. METHODS: CYP2C9 genotypes were identified in 118 DNA samples using real-time PCR (LightCycler) followed by melting curve analysis. All samples were re-tested by validated...

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Detalhes bibliográficos
Principais autores: Burian, Maria, Grösch, Sabine, Tegeder, Irmgard, Geisslinger, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874480/
https://ncbi.nlm.nih.gov/pubmed/12445031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01693.x
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