Enantioselective distribution of albendazole metabolites in cerebrospinal fluid of patients with neurocysticercosis

AIMS: Albendazole (ABZ) is effective in the treatment of neurocysticercosis. ABZ undergoes extensive metabolism to (+) and (−)-albendazole sulphoxide (ASOX), which are further metabolized to albendazole sulphone (ASON). We have investigated the distribution of (+)-ASOX (−)-ASOX, and ASON in cerebros...

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Autors principals: Takayanagui, O M, Bonato, P S, Dreossi, S A C, Lanchote, V L
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874411/
https://ncbi.nlm.nih.gov/pubmed/12207631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01634.x
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