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Determination of the relative bioavailability of salbutamol to the lungs and systemic circulation following nebulization

AIMS: Clinical studies comparing nebulized drug delivery systems could be flawed because of the high doses used. We have compared lung and total systemic delivery of salbutamol from a nebuliser with that from a metered dose inhaler by measuring urinary recovery of drug and its sulphate metabolite. M...

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Autors principals: Silkstone, V L, Corlett, S A, Chrystyn, H
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874406/
https://ncbi.nlm.nih.gov/pubmed/12207629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01632.x
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