Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development

The ubiquitin-like protein, Nedd8, covalently modifies members of the Cullin family. Cullins are the major components of a series of ubiquitin ligases that control the degradation of a broad range of proteins. We found that Nedd8 modifies Cul1 in Drosophila. In Drosophila Nedd8 and Cul1 mutants, pro...

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Detalles Bibliográficos

Publicado en:	Genes Dev
Principais autores:	Ou, Chan-Yen, Lin, Yi-Fan, Chen, Ying-Jiun, Chien, Cheng-Ting
Formato:	Artigo
Idioma:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 2002
Assuntos:	Research Paper
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12231629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1011402
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