Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

AIMS: Bioavailability of orally administered drugs depends on several factors including active excretion, e.g. by P-glycoprotein (PGP), and presystemic metabolism, e.g. by cytochrome P450 3A (CYP3A), in both gastrointestinal tract and liver. Many drugs including saquinavir are substrates of both PGP...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Martin-Facklam, Meret, Burhenne, Jürgen, Ding, Reinhard, Fricker, Ruth, Mikus, Gerd, Walter-Sack, Ingeborg, Haefeli, Walter E
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874336/
https://ncbi.nlm.nih.gov/pubmed/12047481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01595.x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars