Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Transcriptional Activator Rta Is an Oligomeric DNA-Binding Protein That Interacts with Tandem Arrays of Phased A/T-Trinucleotide Motifs

Kaposi's sarcoma associated herpesvirus (KSHV)/human herpesvirus 8 (HHV-8) encodes an immediate early transcriptional activator, Rta, which mediates viral reactivation from latency and lytic viral replication. Here we report the purification and characterizations of HHV-8 Rta and its interactio...

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Bibliographic Details
Main Authors: Liao, Wei, Tang, Yong, Kuo, Yu-liang, Liu, Bao-Ying, Xu, Chi-Jie, Giam, Chou-Zen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC187432/
https://ncbi.nlm.nih.gov/pubmed/12915555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9399-9411.2003
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