Inhibition of basal nitric oxide synthesis increases aortic augmentation index and pulse wave velocity in vivo

AIMS: To investigate the role of basal nitric oxide (NO) production in regulating large artery stiffness in vivo. METHODS: Incremental doses of the NO synthase inhibitor L-N(G)-monomethyl arginine (LNMMA: 0.1, 0.3, 1.0 and 3.0 mg kg(−1) min(−1)) or placebo were infused in eight healthy men. Arterial...

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Autores principales: Wilkinson, Ian B, MacCallum, Helen, Cockcroft, John R, Webb, David J
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science, Ltd 2002
Materias:
Short Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874288/
https://ncbi.nlm.nih.gov/pubmed/11851643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.1528adoc.x
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