Identification of a Mutation in Editing of Defective Newcastle Disease Virus Recombinants That Modulates P-Gene mRNA Editing and Restores Virus Replication and Pathogenicity in Chicken Embryos

Editing of P-gene mRNA of Newcastle disease virus (NDV) enables the formation of two additional proteins (V and W) by inserting one or two nontemplated G residues at a conserved editing site (5′-AAAAAGGG). The V protein of NDV plays an important role in virus replication and is also a virulence fact...

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Detalhes bibliográficos
Main Authors: Mebatsion, Teshome, de Vaan, Leonie T. C., de Haas, Niels, Römer-Oberdörfer, Angela, Braber, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187413/
https://ncbi.nlm.nih.gov/pubmed/12915541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9259-9265.2003
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