Vigabatrin:placental transfer in vivo and excretion into breast milk of the enantiomers

AIMS: Vigabatrin is a new antiepileptic medication consisting of a racemic mixture of 50% active S enantiomer and 50% inactive R enantiomer. Since patients suffering from epilepsy may become pregnant, it is important to understand the extent of placental transfer of such medication. METHODS: During...

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Autors principals: Tran, A, O’Mahoney, T, Rey, E, Mai, J, Mumford, J P, Olive, G
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873959/
https://ncbi.nlm.nih.gov/pubmed/9578192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.t01-1-00693.x
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