Antiviral Activity of Limitin against Encephalomyocarditis Virus, Herpes Simplex Virus, and Mouse Hepatitis Virus: Diverse Requirements by Limitin and Alpha Interferon for Interferon Regulatory Factor 1

Limitin has sequence homology with alpha interferon (IFN-α) and IFN-β and utilizes the IFN-α/β receptor. However, it has no influence on the proliferation of normal myeloid and erythroid progenitors. In this study, we show that limitin has antiviral activity in vitro as well as in vivo. Limitin inhi...

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Auteurs principaux: Kawamoto, Shin-Ichiro, Oritani, Kenji, Asada, Hideo, Takahashi, Isao, Ishikawa, Jun, Yoshida, Hitoshi, Yamada, Masahide, Ishida, Naoko, Ujiie, Hidetoshi, Masaie, Hiroaki, Tomiyama, Yoshiaki, Matsuzawa, Yuji
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC187381/
https://ncbi.nlm.nih.gov/pubmed/12915574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9622-9631.2003
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