Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions

AIMS: The primary objective of this study was to determine whether pharmacokinetic interactions occurred between interferon α-2b (IFN) and ribavirin in patients with chronic hepatitis C infections. Additionally this study assessed the single and multiple-dose pharmacokinetics of ribavirin and IFN, a...

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Bibliografiske detaljer
Main Authors: Khakoo, Salim, Glue, Paul, Grellier, Leonie, Wells, Beverley, Bell, Allan, Dash, Clive, Murray-Lyon, Iain, Lypnyj, David, Flannery, Brian, Walters, Karen, Dusheiko, Geoffrey M
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1998
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873804/
https://ncbi.nlm.nih.gov/pubmed/9862245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00836.x
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