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Population pharmacokinetics and therapeutic response of CGP 56697 (artemether + benflumetol) in malaria patients

AIMS: To investigate the pharmacokinetic and pharmacodynamic properties of artemether and benflumetol in a fixed combination tablet (CGP 56697) and to offer an explanation for the lower than expected cure rate in a Thai clinical trial. METHODS: Two hundred and sixty patients were enrolled into a ran...

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Autores principales: Ezzet, Farkad, Mull, Robert, Karbwang, Juntra
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873796/
https://ncbi.nlm.nih.gov/pubmed/9862244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00830.x
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