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Assessment of hepatic blood flow using continuous infusion of high clearance drugs

AIMS: To provide methods for the translation of the concentration-time profile of highly cleared marker compounds into the underlying clearance and hepatic blood flow profile. METHODS: Continuous infusion of indocyanine green or sorbitol was used to assess the effect of the hepatic blood flow modifi...

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Bibliographic Details
Main Authors: Schoemaker, R C, Burggraaf, J, Cohen, A F
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873547/
https://ncbi.nlm.nih.gov/pubmed/9643619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00711.x
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