Stimulation of T-Helper Cell Gamma Interferon and Immunoglobulin G Responses Specific for Babesia bovis Rhoptry-Associated Protein 1 (RAP-1) or a RAP-1 Protein Lacking the Carboxy-Terminal Repeat Region Is Insufficient To Provide Protective Immunity against Virulent B. bovis Challenge

Rhoptry-associated protein 1 (RAP-1) is a targeted vaccine antigen for Babesia bovis and Babesia bigemina infections of cattle. The 60-kDa B. bovis RAP-1 is recognized by antibodies and T lymphocytes from cattle that recovered from infection and were immune to subsequent challenge. Immunization with...

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Detalhes bibliográficos
Main Authors: Norimine, Junzo, Mosqueda, Juan, Suarez, Carlos, Palmer, Guy H., McElwain, Terry F., Mbassa, Gabriel, Brown, Wendy C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187345/
https://ncbi.nlm.nih.gov/pubmed/12933845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5021-5032.2003
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