Increases in metabolism of valproate and excretion of 6β-hydroxycortisol in patients with traumatic brain injury

AIMS: The objectives of this study were to determine the effect of brain trauma on the multiple pathways of metabolism of valproate and to evaluate the use of the urinary 6β-hydroxycortisol to cortisol ratio in predicting changes in hepatic metabolism induced by brain injury. METHODS: Fourteen patie...

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Detalhes bibliográficos
Main Authors: Anderson, Gail D, Awan, Asaad B, Adams, Carlyn A, Temkin, Nancy R, Winn, H Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873360/
https://ncbi.nlm.nih.gov/pubmed/9491821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00652.x
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