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Insertional Inactivation of pac and rmlB Genes Reduces the Release of Tumor Necrosis Factor Alpha, Interleukin-6, and Interleukin-8 Induced by Streptococcus mutans in Monocytic, Dental Pulp, and Periodontal Ligament Cells

Streptococcus mutans possesses different cell wall molecules, such as protein of the I/II family, the serotype f polysaccharide rhamnose glucose polymer (RGP), and lipoteichoic acid (LTA), which act as adhesins and modulins, allowing S. mutans to colonize teeth and cause dental caries and pulpitis....

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Bibliographic Details
Main Authors: Engels-Deutsch, Marc, Pini, Annelise, Yamashita, Yoshihisa, Shibata, Yukie, Haikel, Youssef, Schöller-Guinard, Marie, Klein, Jean-Paul
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC187322/
https://ncbi.nlm.nih.gov/pubmed/12933861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5169-5177.2003
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