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Traditional Nonsteroidal Anti-Inflammatory Drugs and Postmenopausal Hormone Therapy: A Drug–Drug Interaction?
BACKGROUND: Suppression of prostacyclin (PGI(2)) is implicated in the cardiovascular hazard from inhibitors of cyclooxygenase (COX)-2. Furthermore, estrogen confers atheroprotection via COX-2–dependent PGI(2) in mice, raising the possibility that COX inhibitors may undermine the cardioprotection, su...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1872041/ https://ncbi.nlm.nih.gov/pubmed/17518513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040157 |
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