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Understanding the Slow Depletion of Memory CD4(+) T Cells in HIV Infection

BACKGROUND: The asymptomatic phase of HIV infection is characterised by a slow decline of peripheral blood CD4(+) T cells. Why this decline is slow is not understood. One potential explanation is that the low average rate of homeostatic proliferation or immune activation dictates the pace of a “runa...

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Hlavní autoři: Yates, Andrew, Stark, Jaroslav, Klein, Nigel, Antia, Rustom, Callard, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1872038/
https://ncbi.nlm.nih.gov/pubmed/17518516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040177
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