Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer

We conducted a phase 1 study of 9 pediatric patients with recurrent brain tumors using monocyte-derived dendritic cells pulsed with tumor RNA to produce antitumor vaccine (DC(RNA)) preparations. The objectives of this study included (1) establishing safety and feasibility and (2) measuring changes i...

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Detalhes bibliográficos
Main Authors: Caruso, Denise A., Orme, Lisa M., Neale, Alana M., Radcliff, Fiona J., Amor, Gerlinda M., Maixner, Wirginia, Downie, Peter, Hassall, Timothy E., Tang, Mimi L.K., Ashley, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2004
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1872001/
https://ncbi.nlm.nih.gov/pubmed/15279716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851703000668
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