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O(6)-Benzylguanine suppression of O(6)-alkylguanine-DNA alkyltransferase in anaplastic gliomas
The purpose of the study was to determine the dose of O(6)-benzylguanine (BG) that would suppress O(6)-alkylguanine-DNA alkyltransferase (AGT) activity to undetectable levels in >90% of anaplastic gliomas, as measured 6 h after a 1-h BG infusion. Subjects who were scheduled for surgical resection...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Duke University Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1871964/ https://ncbi.nlm.nih.gov/pubmed/14769137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S115285170300019X |
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