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Phase 2 study of T138067-sodium in patients with malignant glioma: Trial of the National Cancer Institute of Canada Clinical Trials Group
We studied the activity of T138067-sodium in patients with malignant gliomas. T138067-sodium is a unique new chemotherapy agent that inhibits microtubule formation by binding irreversibly and specifically to β(1), β(2,) and β(4) isotypes of β-tubulin, causing cell arrest at G(2)/M and inducing apopt...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Duke University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1871890/ https://ncbi.nlm.nih.gov/pubmed/15831236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704000602 |
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