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DNA-nanotube-induced alignment of membrane proteins for NMR structure determination

Membrane proteins are encoded by 20–35% of genes but represent <1% of known protein structures to date. Thus, improved methods for membrane-protein structure determination are of critical importance. Residual dipolar couplings (RDCs), commonly measured for biological macromolecules weakly aligned...

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Библиографические подробности
Главные авторы: Douglas, Shawn M., Chou, James J., Shih, William M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871839/
https://ncbi.nlm.nih.gov/pubmed/17404217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700930104
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