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Mechanisms of action of rapamycin in gliomas

Rapamycin has previously been shown to be efficacious against intracerebral glioma xenografts and to act in a cytostatic manner against gliomas. However, very little is known about the mechanism of action of rapamycin. The purpose of our study was to further investigate the in vitro and in vivo mech...

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Main Authors: Heimberger, Amy B., Wang, Enze, McGary, Eric C., Hess, Kenneth R., Henry, Verlene K., Shono, Tadahisa, Cohen, Zvi, Gumin, Joy, Sawaya, Raymond, Conrad, Charles A., Lang, Frederick F.
Formato: Artigo
Idioma:Inglês
Publicado: Duke University Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871627/
https://ncbi.nlm.nih.gov/pubmed/15701277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704000420
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