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Effect of the Na-K-2Cl Cotransporter NKCC1 on Systemic Blood Pressure and Smooth Muscle Tone

Studies in rat aorta have shown that the Na-K-2Cl cotransporter NKCC1 is activated by vasoconstrictors and inhibited by nitrovasodilators, contributes to smooth muscle tone in vitro, and is upregulated in hypertension. To determine the role of NKCC1 in systemic vascular resistance and hypertension,...

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Detalhes bibliográficos
Main Authors: Garg, Puneet, Martin, Christopher F., Elms, Shawn C., Gordon, Frank J., Wall, Susan M., Garland, Christopher J., Sutliff, Roy L., O’Neill, W. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871614/
https://ncbi.nlm.nih.gov/pubmed/17259435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01402.2006
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