Effect of the Na-K-2Cl Cotransporter NKCC1 on Systemic Blood Pressure and Smooth Muscle Tone

Studies in rat aorta have shown that the Na-K-2Cl cotransporter NKCC1 is activated by vasoconstrictors and inhibited by nitrovasodilators, contributes to smooth muscle tone in vitro, and is upregulated in hypertension. To determine the role of NKCC1 in systemic vascular resistance and hypertension,...

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Hauptverfasser: Garg, Puneet, Martin, Christopher F., Elms, Shawn C., Gordon, Frank J., Wall, Susan M., Garland, Christopher J., Sutliff, Roy L., O’Neill, W. Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871614/
https://ncbi.nlm.nih.gov/pubmed/17259435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01402.2006
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