Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta

Marrow stromal cells from wild-type mice were infused into transgenic mice that had a phenotype of fragile bones resembling osteogenesis imperfecta because they expressed a human minigene for type I collagen. In mice that were irradiated with potentially lethal levels (700 cGy) or sublethal levels (...

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Main Authors: Pereira, Ruth F., O’Hara, Michael D., Laptev, Alexey V., Halford, Kenneth W., Pollard, Marea D., Class, Reiner, Simon, Daniela, Livezey, Kristin, Prockop, Darwin J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18700/
https://ncbi.nlm.nih.gov/pubmed/9448299
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