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Microbial Reduction of 1,3-Dioxo-2-Methyl-2-(3′-Oxo-6′-Carbomethoxyhexyl)-Cyclopentane to Form 1β-Hydroxy-3-Oxo-2β-Methyl-2α-(3′-Oxo-6′-Carbomethoxy-hexyl)-Cyclopentane, an Intermediate for Steroid Total Synthesis

The rate and extent of stereoselective reduction of 1,3-dioxo-2-methyl-2-(3′-oxo-6′-carbomethoxyhexyl)-cyclopentane to form the 1β-hydroxy-2β-methyl isomer by cultures of Schizosaccharomyces pombe ATCC 2476 was dramatically increased by addition to the fermentation of certain α,β-unsaturated ketones...

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Dades bibliogràfiques
Publicat a:Appl Microbiol
Autors principals: Lanzilotta, Raymond P., Bradley, Dorothy G., Beard, Colin C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1975
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186991/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1115508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.29.3.427-429.1975
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