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Regulation and function of Bcl-2 during differentiation-induced cell death in HL-60 promyelocytic cells.

Polymorphonuclear leukocytes are generated by differentiation of early myeloid precursors. Once fully differentiated, blood neutrophils are programmed to die rapidly and are removed by tissue macrophages. In normal myeloid cells, the death mechanism seems to be coupled to the differentiation pathway...

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Autori principali: Benito, A., Grillot, D., Nuñez, G., Fernández-Luna, J. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869853/
https://ncbi.nlm.nih.gov/pubmed/7856757
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