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p21(WAF-1) reorganizes the nucleus in tumor suppression

Interphasic nuclear organization has a key function in genome biology. We demonstrate that p21(WAF-1), by influencing gene expression and inducing chromosomal repositioning in tumor suppression, plays a major role as a nuclear organizer. Transfection of U937 tumor cells with p21(WAF-1) resulted in e...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Linares-Cruz, Gustavo, Bruzzoni-Giovanelli, Heriberto, Alvaro, Véronique, Roperch, Jean-Pierre, Tuynder, Marcel, Schoevaert, Damien, Nemani, Mona, Prieur, Sylvie, Lethrosne, Florence, Piouffre, Laurence, Reclar, Valérie, Faille, Annick, Chassoux, Danièle, Dausset, Jean, Amson, Robert B., Calvo, Fabien, Telerman, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1131
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