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A Method to Address Differential Bias in Genotyping in Large-Scale Association Studies

In a previous paper we have shown that, when DNA samples for cases and controls are prepared in different laboratories prior to high-throughput genotyping, scoring inaccuracies can lead to differential misclassification and, consequently, to increased false-positive rates. Different DNA sourcing is...

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Detalhes bibliográficos
Main Authors: Plagnol, Vincent, Cooper, Jason. D, Todd, John A, Clayton, David G
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868951/
https://ncbi.nlm.nih.gov/pubmed/17511519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030074
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