Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease

BACKGROUND: Alternative gene transcript splicing permits a single gene to produce multiple proteins with varied functions. Bioinformatic investigations have identified numerous splice variants, but whether these transcripts are translated to functional proteins and the physiological significance of...

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Autors principals: Heinzen, Erin L, Yoon, Woohyun, Weale, Michael E, Sen, Arjune, Wood, Nicholas W, Burke, James R, Welsh-Bohmer, Kathleen A, Hulette, Christine M, Sisodiya, Sanjay M, Goldstein, David B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868939/
https://ncbi.nlm.nih.gov/pubmed/17343748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-3-r32
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