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Interdomain association in fibronectin: insight into cryptic sites and fibrillogenesis

The process by which fibronectin (FN), a soluble multidomain protein found in tissue fluids, forms insoluble fibrillar networks in the extracellular matrix is poorly understood. Cryptic sites found in FN type III domains have been hypothesized to function as nucleation points, thereby initiating fib...

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Bibliografiske detaljer
Main Authors: Vakonakis, Ioannis, Staunton, David, Rooney, Luke M, Campbell, Iain D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868906/
https://ncbi.nlm.nih.gov/pubmed/17464288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601694
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