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Mannan-binding lectin may facilitate the clearance of circulating immune complexes – implications from a study on C2-deficient individuals

Deficiency of both mannan-binding lectin (MBL) and complement components C4 and C2 has been associated with increased risk of systemic lupus erythematosus (SLE). MBL can activate the complement system either through C4 and C2 or directly through C3. Circulating immune complexes (CICs) are believed t...

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Detalhes bibliográficos
Main Authors: Saevarsdottir, S, Steinsson, K, Ludviksson, B R, Grondal, G, Valdimarsson, H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868874/
https://ncbi.nlm.nih.gov/pubmed/17335556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03349.x
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