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The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

Uncommitted (naive) murine CD4(+) T helper cells (Thp) can be induced to differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (T(reg)) phenotypes according to the local cytokine milieu. This can be demonstrated most readily both in vitro and in vivo in murine CD4(+) T cells. The presence...

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Détails bibliographiques
Auteurs principaux: Afzali, B, Lombardi, G, Lechler, R I, Lord, G M
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868863/
https://ncbi.nlm.nih.gov/pubmed/17328715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03356.x
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