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Citrinin induces apoptosis via a mitochondria-dependent pathway and inhibition of survival signals in embryonic stem cells, and causes developmental injury in blastocysts
The mycotoxin CTN (citrinin), a natural contaminant in foodstuffs and animal feeds, has cytotoxic and genotoxic effects on various mammalian cells. CTN is known to cause cell injury, including apoptosis, but the precise regulatory mechanisms of CTN action, particularly in stem cells and embryos, are...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868791/ https://ncbi.nlm.nih.gov/pubmed/17331071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061875 |
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