CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease

The ileal mucosa of Crohn disease (CD) patients is abnormally colonized by adherent-invasive E. coli (AIEC) that are able to adhere to and invade intestinal epithelial cells. Here, we show that CD-associated AIEC strains adhere to the brush border of primary ileal enterocytes isolated from CD patien...

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Main Authors: Barnich, Nicolas, Carvalho, Frédéric A., Glasser, Anne-Lise, Darcha, Claude, Jantscheff, Peter, Allez, Matthieu, Peeters, Harald, Bommelaer, Gilles, Desreumaux, Pierre, Colombel, Jean-Frédéric, Darfeuille-Michaud, Arlette
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2007
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868786/
https://ncbi.nlm.nih.gov/pubmed/17525800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30504
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