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The L-Isoaspartyl-O-Methyltransferase in Caenorhabditis elegans Larval Longevity and Autophagy

The protein L-isoaspartyl-O-methyltransferase, coded by the pcm-1 gene in Caenorhabditis elegans, participates in the repair of age-damaged proteins. We tested the ability of pcm-1-deficient nematodes to survive starvation stress as developmentally-arrested L1 larvae. We found that pcm–1 mutant L1 l...

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Autors principals: Gomez, Tara A., Banfield, Kelley L., Trogler, Dorothy M., Clarke, Steven G.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868680/
https://ncbi.nlm.nih.gov/pubmed/17187774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.11.023
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